It’s Bunsen and Cosmo’s Friend-iversary, so Bunsen excitedly takes Mikey to meet Cosmo in Dimmsdale, while Amanda secretly follows, and teams up with Mr. Crocker.
- Jeremy Rowley as Bunsen, Mikey's Dad, Portraits
- Ben Giroux as Mikey Munroe
- Kari Wahlgren as Amanda Killman, Mikey's Mom, Portraits
- Carlos Alazraqui as Denzel Crocker, Snapping Toilet, Trolls
- Susanne Blakeslee as Wanda, Mrs. Turner
- Daran Norris as Cosmo, Mr. Turner, Trolls
- Phil LaMarr as Boodles, Bunsen's House
- Tara Strong as Timmy Turner, Shopper
- This episode is a crossover with "The Fairly OddParents".
- This is the first half-hour episode in the series by production order. However, "Tooth or Consequences", another half-hour episode, premiered first.
- The episode's title is a pun on the phrase "best of friends".
- This episode revealed that Bunsen has magical portals to every world.
- This episode is dedicated to the memory of Kevin Iwaki.
- This episode reveals that Mikey is a grade older than Timmy Turner.
- Bunsen sings The Fairly OddParents theme song.